In an interview for CBS This Morning late actor and comedian Bob Saget opened up about the loss of his older sister and raising awareness about the disease Scleroderma. The interview which was filmed back in December features the “Full House” star and his more serious and sensitive side as he discusses the disease that took the life of his older sister in 1994 and his fight to help people with the disease.

Scleroderma means hard skin. It’s an autoimmune disease where excess collagen causes tissue to lose its elasticity. Symptoms include tightening of the skin finger and toe pain, arthritis, muscle weakness, and trouble swallowing.